Searchable abstracts of presentations at key conferences on calcified tissues

ba0001pp272 | Genetics | ECTS2013

Comparison of gene expression in osteoblasts from patients of Polynesian and Caucasian ethnicities

Naot Dorit , Bava Usha , Choi Ally , Callon Karen , Pitto Rocco , Bentley Jarome , Gamble Greg , Cornish Jillian

Polynesians have higher bone mineral density and lower rate of hip fracture compared to age-matched Caucasian in New Zealand, and anecdotal evidence suggests that bones of Polynesian patients heal much faster than those of Caucasians. We compared gene expression in osteoblasts cultured form bone samples taken from patients of Polynesian and Caucasian origin, in order to identify genes and pathways that contribute to the greater density and accelerated healing of Polynesian bon...